Early warning of MIB episode based on gene abundance and expression in drinking water reservoirs

How to know when MIB episode comes?
Gene may tell you. Try
qPCR with mic gene!
2-methylisoborneol (MIB)
MIB synthesis gene
Pseudanabaena
Prediction
Light intensity
Gene expression
Reservoir

WR2023a: Tengxin Cao, Ming Su, Min Yang, et. al. Early warning of MIB episode based on gene abundance and expression in drinking water reservoirs. Water Research 2023;231:119667. 10.1016/j.watres.2023.119667.

Authors
Affiliations

Tengxin Cao

Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

Sino-Danish College, University of Chinese Academy of Sciences

University of Chinese Academy of Sciences

Jiao Fang

Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

Zeyu Jia

Yangtze Eco-Environment Engineering Research Center, China Three Gorges Corporation

Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

Yiping Zhu

Shanghai Chengtou Raw Water Co. Ltd.

Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

National Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

University of Chinese Academy of Sciences

Qi Zhang

Institute of Hydrobiology, Chinese Academy of Sciences

Yichao Song

Shanghai Chengtou Raw Water Co. Ltd.

Jianwei Yu

Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

National Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

University of Chinese Academy of Sciences

National Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

University of Chinese Academy of Sciences

Published

Mar 1, 2023

Doi

Abstract

Cellular 2-methylisoborneol (MIB) yield of cyanobacteria varies under different conditions according to culture studies and field investigations, the causal mechanism remains unclear and results in ineffective MIB prediction. Through an intensive field survey during an MIB episode produced by Pseudanabaena cinerea in QCS reservoir, we demonstrated that MIB synthesis (mic) gene abundance (DNA) and expression (RNA) might be useful as parameters for early warning of MIB production. It was found that the abundance of mic DNA and RNA peaked ahead of MIB concentrations by 10 and 7 days, respectively. In addition, the RNA abundance (R2 = 0.45, p < 0.01) showed a slightly higher correlation with MIB compared to DNA abundance (R2 = 0.37, p < 0.01), suggesting that the conditions for the growth of Pseudanabaena cinerea might be slightly different from those for mic gene expression, which was verified by a culture experiment. The highest cell growth was obtained under 36 μmol photons m-2 s-1, while the highest cellular MIB yield and mic gene expression level were obtained under 85 μmol photons m-2 s-1. Our results clearly supported that light intensity was the virtual regulator governing the mic gene expression within the controlled culture experiment and the actual MIB episode in the reservoir. Besides these results, we developed an early warning model using mic gene abundance as an indicator of MIB episodes, which was verified in two other reservoirs. Our findings highlight the effect of light intensity on mic gene expression and MIB synthesis and provide an early warning tool targeting MIB episode prediction, which therefore should be of importance for source water authorities.

Graphical abstract

Citation

Add to Zotero

@Article{cao2023early,
    title       = {Early warning of MIB episode based on gene abundance and expression in drinking water reservoirs},
    author      = {Tengxin Cao and Jiao Fang and Zeyu Jia and Yiping Zhu and Ming Su and Qi Zhang and Yichao Song and Jianwei Yu and Min Yang},
    year        = 2023,
    journal     = {Water Research},
    volume      = 231,
    pages       = 119667,
    url         = {https://www.sciencedirect.com/science/article/pii/S0043135423001021},
    issn        = {0043-1354},
    doi         = {10.1016/j.watres.2023.119667}
}